The Pro series of NAS from ReadyNAS (Netgear) support iSCSI out of the box. But the NV+ 4disk unit does not. However - a third party plugin is available. Let's look at what is needed to get iSCSI connections between the ReadyNAS NV+ and an iMac running Snow Leopard.
Just a short reminder - the list of paths that path_helper (/usr/libexec/path_helper is called from /etc/profile) is stored in /etc/paths. Just add /usr/local/bin at the top of the file.